UP000002149
Proteome Details
| Accession | UP000002149  |
|---|---|
| Description | Cryptococcus neoformans sexual reproduction results in the formation of basidia and basidiospores - microscopic, spore-producing, club-shaped structures. This makes it more closely related to wood rotting fungus than other pathogenic yeasts such as Candida albicans. Cryptococcus neoformans is a yeast which can infect humans, usually resulting in lung infection. In immuno-compromised subjects such as those with AIDS the yeast can invade the central nervous system and brain causing meningitis and encephalitis. Serotyping is used to identify one of four types A, B, C and D, where type A is C. neoformans var. grubii, types B and C are C. neoformans var. gattii and type D is C. neoformans var. neoformans. Cryptococcus is found in soil, associated with certain trees and bird excrement and the distribution of types varies globally. The genome was published in 2005. It consists of 14 chromosomes containing 19Mb with approximately 6,500 predicted protein-coding genes. The genome is rich in transposons, possibly driving karyotype instability and phenotypic variation. |
| Scientific Name | Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) |
| Strain | JEC21 / ATCC MYA-565 |
| Synonyms | Filobasidiella neoformans |
| Taxonomy ID | 214684  |
| Lineage | >Fungi>Basidiomycota>Agaricomycotina>Tremellomycetes>Tremellales>Cryptococcaceae>Cryptococcus |
| # Genes | 6,604 |
| # Proteins | 6,743 |
Summary & Statistics
Predicted NoLS
Protein Length
WOLFPSORT Prediction