Nucleolar Localized Proteins

Nucleolar localized proteins available in the database.

Q6C8H2

Protein Details
Accession Q6C8H2    Localization Confidence High Confidence Score 18.5
NoLS Segment(s)
PositionSequenceProtein Nature
41-67NEQPRKFKNRVAKPKDNGKPKVKKARVBasic
NLS Segment(s)
PositionSequence
45-66RKFKNRVAKPKDNGKPKVKKAR
86-98GAKKALRGKKGKK
134-192REQKRKEIEKREAEKEAEIEQKKKEIKKTSRGKSADKVQKKMEELKKKEEGKGNSKKKS
Subcellular Location(s) nucl 23.5, cyto_nucl 12.5
Family & Domain DBs
InterPro View protein in InterPro  
IPR037650  Loc1  
Gene Ontology GO:0005730  C:nucleolus  
GO:0030687  C:preribosome, large subunit precursor  
GO:0101031  C:protein folding chaperone complex  
GO:0042802  F:identical protein binding  
GO:0003729  F:mRNA binding  
GO:0000480  P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  
GO:0000447  P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  
GO:0000472  P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  
GO:0008298  P:intracellular mRNA localization  
GO:0051028  P:mRNA transport  
GO:0017148  P:negative regulation of translation  
GO:0042273  P:ribosomal large subunit biogenesis  
GO:0000055  P:ribosomal large subunit export from nucleus  
KEGG yli:YALI0D19624g  -  
Amino Acid Sequences MVPKRFRKENAGAREVKSEVFGDKKARNQLAHTSKNYDNANEQPRKFKNRVAKPKDNGKPKVKKARVYTEKELGIPKLNTAIDPEGAKKALRGKKGKKFVDNDQMNLLVSIVNEKIDSRNASKLEKARQLEMIREQKRKEIEKREAEKEAEIEQKKKEIKKTSRGKSADKVQKKMEELKKKEEGKGNSKKKSVSFA
FASTA Sequence
with NoLS information
AlphaFold Structure
with highlighted NoLS
NoLS Predictions per Residue
Residue Number Score
1 0.64
2 0.56
3 0.46
4 0.38
5 0.29
6 0.25
7 0.24
8 0.25
9 0.27
10 0.31
11 0.37
12 0.43
13 0.47
14 0.46
15 0.46
16 0.53
17 0.56
18 0.59
19 0.56
20 0.54
21 0.5
22 0.55
23 0.53
24 0.44
25 0.39
26 0.39
27 0.45
28 0.47
29 0.46
30 0.49
31 0.54
32 0.6
33 0.59
34 0.58
35 0.58
36 0.62
37 0.71
38 0.72
39 0.75
40 0.74
41 0.82
42 0.84
43 0.83
44 0.81
45 0.8
46 0.8
47 0.79
48 0.84
49 0.79
50 0.78
51 0.76
52 0.78
53 0.77
54 0.75
55 0.71
56 0.66
57 0.61
58 0.55
59 0.49
60 0.39
61 0.35
62 0.27
63 0.21
64 0.19
65 0.18
66 0.16
67 0.16
68 0.16
69 0.12
70 0.13
71 0.14
72 0.12
73 0.12
74 0.12
75 0.11
76 0.19
77 0.23
78 0.3
79 0.37
80 0.45
81 0.53
82 0.63
83 0.66
84 0.64
85 0.64
86 0.63
87 0.64
88 0.57
89 0.49
90 0.41
91 0.37
92 0.3
93 0.26
94 0.19
95 0.09
96 0.07
97 0.07
98 0.06
99 0.05
100 0.05
101 0.06
102 0.07
103 0.09
104 0.12
105 0.13
106 0.18
107 0.19
108 0.21
109 0.25
110 0.29
111 0.34
112 0.38
113 0.38
114 0.35
115 0.4
116 0.39
117 0.39
118 0.42
119 0.46
120 0.45
121 0.49
122 0.48
123 0.47
124 0.52
125 0.57
126 0.57
127 0.57
128 0.6
129 0.65
130 0.7
131 0.7
132 0.68
133 0.62
134 0.54
135 0.46
136 0.41
137 0.39
138 0.36
139 0.34
140 0.31
141 0.37
142 0.41
143 0.45
144 0.49
145 0.51
146 0.57
147 0.64
148 0.73
149 0.75
150 0.79
151 0.79
152 0.77
153 0.75
154 0.77
155 0.77
156 0.75
157 0.72
158 0.68
159 0.7
160 0.68
161 0.7
162 0.69
163 0.69
164 0.67
165 0.69
166 0.72
167 0.7
168 0.73
169 0.71
170 0.69
171 0.69
172 0.74
173 0.76
174 0.75
175 0.75
176 0.73